While many physicians (and experts in heart disease and cholesterol) are familiar with the benefits of statins, they are often unfamiliar with the adverse experiences that many people have reported. These include: muscle pain, muscle weakness, fatigue, peripheral neuropathy, memory/thinking problems, and mood/personality changes among other symptoms.
Previously, we conducted a "randomized controlled trial" of persons living in San Diego, examining effects of low dose statins on thinking, mood, behavior, and quality of life. This study was funded by the National Institutes of Health. Analysis and study reports of our randomized trial are ongoing.
We are currently undertaking a separate, observational study, The Statin Effects Study. We are interested in the experiences of people presently or formerly on statins, who have noticed any side effects (or benefits) while on these drugs. We are also interested in hearing from people who did not notice any change in order to to help identify characteristics that may predict risks and benefits while on statins.
This observational study was previously partially funded by the Robert Wood Johnson Faculty Scholar Award. Currently, this effort is without funding and relies on volunteer time and kind donations to help cover costs (we do not accept the financial support of drug companies). Visit our "Contribute" page to learn more.
● February 13, 2008 Update ●
Our study was recently mentioned in the New York Times and The Wall Street Journal about statins and memory loss. Dr. Beatrice Golomb was also interviewed on Good Morning America. The video, located on the right of the screen, can be seen here.
Articles published from the UCSD Statin Effects Study:
● January 10, 2008 Update ●
an abstract, entitled "Simvastatin but Not Pravastatin Affects Sleep:
Findings from the UCSD Statin Study," at the November 2007 American Heart
Association annual meeting. You can read more about it at
Today and/or contact us
and we will send you a copy of the abstract!
● August 24, 2007 Update ●
We had a publication, entitled " Physician Response to Patient Reports of Adverse Drug Effects," in the August issue of the journal, Drug Safety. You can read more about the article in the Washington Post and/or contact us!
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Please email The UCSD Statin Study for any questions regarding this website. Last updated 02/13/08.